Histopathologic examination creates a better understanding of the manifestations of diseases in the ears.

 

 

 

 

 

 

 

 

 

 

 

 

Microscopic studies of a range of otic structures, such as the tympanic membrane, middle/inner ear, eustachian tube, and stria vascularis, reveal changes that occur from medications to treat auditory dysfunction, and from toxicity of drugs and chemicals.

Turner Scientific is pleased to offer general histopathologic services through a partnership with Kenneth A. Schafer, DVM, PhD, DACVP. Dr. Schafer received his PhD in pathobiology in 1998, and has since held several prominent roles in the pharmaceutical industry and for theSociety for Toxicologic Pathology. He is a frequent speaker at international meetings and has published several regulatory position papers and book chapters. He is currently a staff pathologist at Vet Path Services (http://vetpathservicesinc.com/), an independent contracthistopathology lab in Ohio.

Chinchilla hair cells, stria vascularis – 20x

General pathology capabilities through Vet Path Services include histologic processing and evaluation of the inner, middle, and external ear for multiple species in support of GLP toxicology studies:

  • Longitudinal sections of external and middle ear are processed and stained with hematoxylin and eosin following routine procedures to allow evaluation of multiple structures within these complex 3-dimensional structures.  

  • Inner ears (tympanic bulla with cochlea and vestibular structures) are processed, step sectioned, and stained with hematoxylin and eosin. Cochleas are oriented to capture mid-modiolar sections to allow for detailed examination of all parts of the inner ear.