“Normal” hearing at any frequency in humans is defined as the ability to perceive a sound at a
volume of 20 dB or less. Hearing loss is not considered to be “severe” until the volume required
to perceive a sound reaches a threshold of 70 dB, and “profound” hearing loss...
It is well known among auditory scientists and clinicians that hearing loss from any cause,
including ototoxicity, has substantial psychosocial consequences on adults, such as
communication difficulties, social isolation, social stigmatization, cognitive impairment, lo...
Few members of the pharmacology and biotechnology communities would deny that hearing is
generally important. However, when considering the necessity for ototoxicity screening and
prevention, many drug developers and regulatory experts assume that only severe